منابع مشابه
NLRP7 in the spectrum of reproductive wastage: rare non-synonymous variants confer genetic susceptibility to recurrent reproductive wastage.
BACKGROUND NLRP7 mutations are responsible for recurrent molar pregnancies and associated reproductive wastage. To investigate the role of NLRP7 in sporadic moles and other forms of reproductive wastage, the authors sequenced this gene in a cohort of 135 patients with at least one hydatidiform mole or three spontaneous abortions; 115 of these were new patients. METHODS/RESULTS All mutations w...
متن کاملReproductive wastage and the evolution of genetic systems.
An outstanding problem for evolutionary biology is the maintenance of anisogamous sex in the face of the ostensible twofold reproductive advantage accruing to parthenogenetic females that do not produce male offspring (Williams, 1975; Maynard Smith, 1978; Bell, 1982). Conventional solutions are sought in terms of cryptic advantages to sex involving variable environments, genetic load, and DNA d...
متن کاملMutations in NLRP5 are associated with reproductive wastage and multi-locus imprinting disorders in humans
Human-imprinting disorders are congenital disorders of growth, development and metabolism, associated with disturbance of parent of origin-specific DNA methylation at imprinted loci across the genome. Some imprinting disorders have higher than expected prevalence of monozygotic twinning, of assisted reproductive technology among parents, and of disturbance of multiple imprinted loci, for which ...
متن کاملConsanguinity, fertility, reproductive wastage, infant mortality and congenital malformations in Jordan.
OBJECTIVES Consanguinity is a wide spread practice in Jordan. The objective of this study is to explore the health effects of consanguinity, in particular fertility, reproductive wastage, infant mortality and congenital malformations. METHODS A stratified 2 stage cluster sample of 1867 married couples, representative of all population groups and all geographic locations of Jordan were randoml...
متن کاملA Study of Reproductive Wastage among Commerical Sheep Flocks Grazing Oestrogenic Pastures in South Western Australia
Reproductive wastage was investigated over two seasons in ten Merino flocks grazing pastures based on oestrogenic subterranean clover. Only 65 percent of ewes were served during the first 16 days of joining. Ovulation rates were low, averaging 1.13. Fertilization rates (73%) were low when compared with flocks unaffected by oestrogenic pastures. Embryonic mortality varied considerably between pr...
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ژورنال
عنوان ژورنال: American Journal of Public Health and the Nations Health
سال: 1957
ISSN: 0002-9572
DOI: 10.2105/ajph.47.12.1542